The story kicks in when a young woman named (Hannah Ware) discovers that she might be the key to finding her missing father – the creator of the Agent 47 program. Meanwhile, a sinister corporation called Sinthea is hunting her to unlock the secrets of creating super-soldiers. 47 must protect Katia while eliminating threats from both Sinthea and a relentless agent named John Smith (Zachary Quinto), who has his own agenda.